That's true that this resistor have negative impact on sound quality. You can run your 6E5P without it as long as you do not get parazitic oscillation. Just connect screen grid and plate electrodes right on tube socket, using shortest possible cable.
By the way, i've tried using 6E5P without any biasing -- 100 V on plate, 0 V on grid. This way 6E5P sounds much better (to say the least) than with any biasing method i was trying (but i didn't tried yours, actually). As long as your source can drive it, you wouldn't get any distortion, but exactly the opposite -- very clean and very live sound.
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